If insufficient ADH is produced in the liver the body will not be able to metabolize alcohol. Acetaldehyde causes those really uncomfortable symptoms like nausea and headaches.

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Usually the body breaks down alcohol and its eventually eliminated from the body entirely.

Why do i feel sick after one drink. However taking too much water can make your stomach feel very uncomfortable and this can worsen nausea. Some people lack ALDH which is often associated with facial flushing sweating. If natural or plain water makes.
Those with alcohol intolerance can usually only break down alcohol partly turning it into a harmful chemical called acetaldehyde. Usually nausea is a symptom of dehydration. A second enzyme aldehyde dehydrogenase ALDH also plays a role in metabolism.

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